Hematology/Oncology

Navigating Risk-Based Skin Check Intervals for incidentally found Keratinocyte Carcinomas in a Targeted Melanoma Screening Project
Neeraja Thirukkumaran1,2, Amelia Smit3, Maria Paula Senna4, Bruna Gallo1, Gabriella Parsons2, Methmi Perera5, Terence Wong1,5, Serigne Lo1,5, Pascale Guitera1,5, Bruna Gouveia1, Christoph Sinz1, Anne Cust*1,3, Linda K Martin*1,2,3*Joint final author Affiliations: Melanoma Institute Australia, University of New South Wales1.            Melanoma Institute Australia,2.            School of...
Research
Establishment and comparison of two-dimensional and three-dimensional models of gliomas
Alexandra Gee, Dr Ashraf Zaman, Professor Joseph Powell, Madhavi Pandya, Dr Walter Muskovic, Emily Holton Introduction: Diffuse gliomas are incurable primary neoplasms that originate in supportive glial cells of the central nervous system and are the most common primary brain tumours in adults. Gliomas...
Research
PARPi in Advanced Ovarian Cancer; Does it Prolong Survival?
Ashley McMurray, Chantelle Burl, Dr Kate Levett, Dr Ekavi Georgousopoulou Background : Ovarian cancer is the sixth leading cause of cancer-related mortality and the second most lethal gynaecological cancer affecting Australian women. Poor prognosis for advanced ovarian cancer necessitated development of novel drug therapies...
Research
Characterising a new target for the treatment of Glioblastoma Multiforme
Olivia Taylor, Joshua Brzozowski, Kathryn Skelding Background Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumour in humans. The median survival for GBM patients is 10-11 months and has remained static for decades, demonstrating an urgent need to investigate new targets...
Research
Intrathyroidal parathyroid carcinoma causing acute severe pancreatitis: an uncommonly used localisation technique
Erica Dean, Nina-Marie King, Jeff Donlon*, Andrew Thompson Case Report A 40-year-old lady presented with a fluctuating level of consciousness, severe hypercalcaemia, hyperglycaemia, pancreatitis and a right ankle fracture. With a provisional diagnosis of primary hyperparathyroidism, ultrasound and parathyroid-protocol CT were performed, but both...
Research
The role of eculizumab in catastrophic antiphospholipid syndrome
Julia Fattore and Elizabeth Dalton Background Catastrophic antiphospholipid syndrome is a potentially fatal and rare manifestation of antiphospholipid syndrome (APS). It occurs in 1% of APS affected individuals and carries significant mortality. In this report, we discuss the clinical history, investigations and response to...
Research
Role of neoadjuvant radiotherapy and immediate autologous breast reconstruction: from a breast surgeon’s perspective
Nina-Marie King (MBBS), David Littlejohn (MBBS, FRACS) Abstract Neoadjuvant chemotherapy has an established role in breast cancer for patients who are suitable for immediate autologous tissue breast reconstruction however, the role of neoadjuvant radiotherapy is not as well defined. Short course radiotherapy (typically three...
Research
Pneumatosis cystoides coli in a patient with 
Stage IV diffuse large B cell lymphoma

Dr Gabriel Atan Sanchez, Dr William Macfaul, Dr Steven Schlichtemeier Summary A 49-year-old female with a background of stage IV diffuse large B-cell lymphoma and subsequent graft-versus-host disease from a bone marrow transplant.  Presented to a rural referral hospital in New South Wales, Australia...
Research
The natural history of untreated breast carcinoma metastatic to the eyelids: A case report
Digby W Allen,1,2 William Boneham,1 Brent Skippen,1,2  1. Wagga Wagga Base Hospital, Wagga Wagga, NSW,  Australia2. Wagga Wagga Rural Clinical School, School of Medicine, The University of New South Wales, Wagga Wagga, NSW,  Australia Abstract Metastases to the eyelids are rare and most frequently...
Research
Characterising cell intrinsic and whole body metabolic effects of metformin in prostate cancer
Background Metformin inhibits PCa growth; however, its mechanism of action has been controversial. Cancer cells display altered metabolism which fuels their proliferation. The resulting metabolites could play a role in oncogenic signalling or serve as potential biomarkers for advanced PCa. We therefore aimed to:...
Research

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Latest Articles

April, 2025
Preliminary Analysis of Telehealth vs. In-Person Preoperative Consultations and Their Impact on Immediate Bariatric Surgery Outcomes
Swazi Sharma1, Dr Alexa Seal1, Dr Katherine Smith2, Simeon Moore1, Peter Sheeran 1 1. University of Dame Australia (Rural Clinical School – Wagga Wagga) 2. Murrumbidgee Local Health District...
April, 2025
Training and Sustaining Rural Anaesthetists: Insights from a 12-Month Audit of Paediatric General Anaesthetics in Wagga Wagga
Billy Poulden, Dr Judy Killen Introduction: Access to high quality paediatric general anaesthesia (GA) is fundamental to the provision of surgical services in rural areas. Paediatric anaesthesia is a...
April, 2025
Diabetic Foot Disease – A Public Health Issue for Australia
Authors: Peter Sheeran1, Prof. James Charles2, Gerarda Henneken3, Brett MacCue41. JMO, Wagga Wagga Base Hospital MHLD, 2. Director, First Peoples Health Unit, Pro Vice Chancellor (Health), Griffith University, 3....
April, 2025
An Audit of Essential Difficult Airway Trolley Equipment in Selected Regional NSW Hospitals
Patrick Lay, Stuart Lawrie, and Anthony Gray Introduction: In 2021, the Australian and New Zealand College of Anaesthetists (ANZCA) updated its Guideline on Equipment to Manage Difficult Airways1 to...
April, 2025
The Rise of new age technologies in laparoscopic training models: a systematic review
Christopher Katsinas Background Minimally invasive surgery (MIS) has many benefits, such as: reduced post-operative pain, improved aesthetic outcomes and shorter length-of-stay. The challenge of laparoscopic surgery is the high...
April, 2025
Substance Use and Perceptions of Safety: Insights from a National Indigenous Youth Cohort
Heidi Starr Background: Young people who smoke or drink alcohol are often viewed as making a conscious choice, with little recognition of the role that feelings of safety—or the...