Hematology/Oncology
Olivia Taylor, Joshua Brzozowski, Kathryn Skelding Background Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumour in humans. The median survival for GBM patients is 10-11 months and has remained static for decades, demonstrating an urgent need to investigate new targets...
Research
Erica Dean, Nina-Marie King, Jeff Donlon*, Andrew Thompson Case Report A 40-year-old lady presented with a fluctuating level of consciousness, severe hypercalcaemia, hyperglycaemia, pancreatitis and a right ankle fracture. With a provisional diagnosis of primary hyperparathyroidism, ultrasound and parathyroid-protocol CT were performed, but both...
Research
Julia Fattore and Elizabeth Dalton Background Catastrophic antiphospholipid syndrome is a potentially fatal and rare manifestation of antiphospholipid syndrome (APS). It occurs in 1% of APS affected individuals and carries significant mortality. In this report, we discuss the clinical history, investigations and response to...
Research
Nina-Marie King (MBBS), David Littlejohn (MBBS, FRACS) Abstract Neoadjuvant chemotherapy has an established role in breast cancer for patients who are suitable for immediate autologous tissue breast reconstruction however, the role of neoadjuvant radiotherapy is not as well defined. Short course radiotherapy (typically three...
Research
Dr Gabriel Atan Sanchez, Dr William Macfaul, Dr Steven Schlichtemeier Summary A 49-year-old female with a background of stage IV diffuse large B-cell lymphoma and subsequent graft-versus-host disease from a bone marrow transplant. Presented to a rural referral hospital in New South Wales, Australia...
Research
Digby W Allen,1,2 William Boneham,1 Brent Skippen,1,2 1. Wagga Wagga Base Hospital, Wagga Wagga, NSW, Australia2. Wagga Wagga Rural Clinical School, School of Medicine, The University of New South Wales, Wagga Wagga, NSW, Australia Abstract Metastases to the eyelids are rare and most frequently...
Research
Background Metformin inhibits PCa growth; however, its mechanism of action has been controversial. Cancer cells display altered metabolism which fuels their proliferation. The resulting metabolites could play a role in oncogenic signalling or serve as potential biomarkers for advanced PCa. We therefore aimed to:...
Research
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Latest Articles
Cost-Effective Analysis of Inflammatory Bowel Disease Models of Care, A Rural Perspective
Dr Thomas Skinner, BSci, M.D. Dr Symret Singh, BCom M.D. , Dr Nishmi Gunasingam Introduction Unlike many chronic conditions, Inflammatory Bowel Disease (IBD) are often...
Can artificial intelligence play a role in the analysis of non-gated, non-cardiac CT?
Jack Evans, Professor Joseph Suttie Abstract The rapid development of artificial intelligence (AI) has offered an opportunity to improve processing time and diagnostic accuracy of radiological images (1). Deep...
Asthma Morbidity and its Association with Socioeconomic Status in the Australian Population
Dr. Matin Zohoori Niya, Dr. Joanne Hart, Dr. Rajneesh Kaur Background Asthma Australia reports that prevalence of asthma is highest among people living in the lowest socioeconomic areas. Studies...
The Many Fronts of Heart Failure Monitoring – An Observational Study into Heart Failure Patients using Right Heart Catheterisation and Pulse Wave Analysis
Billy Poulden, Dr Audrey Adji, Professor Christopher Hayward Introduction Heart failure (HF) is a condition that occurs when a person’s heart is unable to pump enough blood to adequately...
Outcomes of Telepsychiatry in Australia, a clinical review
Helen Devery and Peter Sheeran Introduction Use of telephone and videoconferencing technologies by psychiatrists is a frequently proposed solution to address lack of resourcing and staff shortages in regional...